Hernan Carol Selected Research

Liposomes (Liposome)

1/2015

Efficacy of CPX-351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program.

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Hernan Carol Research Topics

Disease

54	Neoplasms (Cancer) 01/2019 - 12/2007
19	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2017 - 01/2008
16	Leukemia 01/2019 - 09/2009
8	Neuroblastoma 01/2017 - 06/2008
6	Ewing Sarcoma (Sarcoma, Ewing) 02/2015 - 06/2008
6	Osteosarcoma (Osteogenic Sarcoma) 12/2012 - 06/2008
5	Glioblastoma (Glioblastoma Multiforme) 01/2014 - 06/2008
5	Rhabdomyosarcoma 08/2012 - 06/2008
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2016 - 06/2008
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 09/2015 - 09/2014
2	Wilms Tumor (Wilm's Tumor) 08/2012 - 12/2009
2	Hypoxia (Hypoxemia) 09/2011 - 01/2011
2	Rhabdoid Tumor (Rhabdoid Tumors) 12/2009 - 06/2008
1	Thrombocytopenia (Thrombopenia) 01/2016
1	Myeloid Leukemia (Leukemia, Myelocytic) 10/2012
1	Lymphoma (Lymphomas) 04/2012
1	Hyperalgesia 10/2011
1	Inflammation (Inflammations) 10/2011

Drug/Important Bio-Agent (IBA)

28	N- propyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (PPTP)IBA 01/2017 - 12/2007
4	Vincristine (Oncovin)FDA LinkGeneric 09/2015 - 12/2007
4	ProdrugsIBA 09/2015 - 01/2011
3	MLN 8237IBA 01/2019 - 07/2010
3	navitoclaxIBA 01/2016 - 06/2008
3	PR-104IBA 09/2015 - 01/2011
2	Dexamethasone (Maxidex)FDA LinkGeneric 09/2015 - 01/2010
2	Biomarkers (Surrogate Marker)IBA 09/2015 - 09/2014
2	Asparaginase (Elspar)FDA Link 09/2015 - 01/2012
2	PR-104AIBA 09/2015 - 09/2011
2	talazoparibIBA 02/2015 - 01/2015
2	Temozolomide (Temodar)FDA LinkGeneric 02/2015 - 05/2013
2	Proteins (Proteins, Gene)FDA Link 06/2012 - 07/2008
2	Topotecan (Hycamtin)FDA LinkGeneric 02/2012 - 05/2010
2	Sirolimus (Rapamycin)FDA Link 01/2010 - 04/2008
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2017
1	PND 1186IBA 01/2017
1	CBLC137IBA 01/2017
1	Chimeric Antigen ReceptorsIBA 11/2016
1	AntigensIBA 11/2016
1	purineIBA 03/2016
1	Exportin 1 ProteinIBA 02/2016
1	selinexorIBA 02/2016
1	birinapantIBA 01/2016
1	venetoclaxIBA 01/2016
1	Mechlorethamine (Nitrogen Mustard)FDA Link 09/2015
1	Phosphates (Orthophosphate)IBA 09/2015
1	EstersIBA 09/2015
1	BAL27862IBA 06/2015
1	lisavanbulinIBA 06/2015
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 02/2015
1	EnzymesIBA 02/2015
1	Janus Kinase InhibitorsIBA 02/2015
1	AZD 1480IBA 02/2015
1	Janus KinasesIBA 02/2015
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2015
1	Liposomes (Liposome)IBA 01/2015
1	CPX-351IBA 01/2015
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2015
1	Daunorubicin (Cerubidine)FDA LinkGeneric 01/2015
1	sapanisertibIBA 08/2014
1	nirogacestatIBA 08/2014
1	quisinostatIBA 02/2014
1	Polo-Like Kinase 1IBA 01/2014
1	BI 6727IBA 01/2014
1	eribulin FDA Link 08/2013
1	Antimitotic AgentsIBA 08/2013
1	DNA (Deoxyribonucleic Acid)IBA 05/2013
1	XL147IBA 05/2013
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 05/2013
1	coltuximab ravtansineIBA 04/2013
1	Immunoconjugates (Immunoconjugate)IBA 04/2013
1	RG7112IBA 04/2013
1	Maytansine (Maitansine)IBA 04/2013
1	dinaciclibIBA 12/2012
1	SGI 1776IBA 10/2012
1	MK 2206IBA 09/2012
1	pevonedistatIBA 08/2012
1	JNJ 26854165IBA 08/2012
1	(2,4- dihydroxy- 5- isopropylphenyl)- (5- (4- methylpiperazin- 1- ylmethyl)- 1,3- dihydroisoindol- 2- yl)methanoneIBA 07/2012
1	GSK923295IBA 06/2012
1	KinesinsIBA 06/2012
1	2,2- dimethyl- N- (6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- N'- (2,2,3,3,3- pentafluoropropyl)malonamideIBA 05/2012
1	LCL161IBA 04/2012
1	Genz-644282IBA 02/2012
1	Messenger RNA (mRNA)IBA 02/2012
1	Mechanistic Target of Rapamycin Complex 2IBA 02/2012
1	Mechanistic Target of Rapamycin Complex 1IBA 02/2012
1	(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA 02/2012
1	AnthracyclinesIBA 01/2012
1	GlucocorticoidsIBA 01/2012
1	Aurora Kinase AIBA 11/2011
1	Lenalidomide (CC 5013)FDA Link 10/2011
1	Aldo-Keto ReductasesIBA 09/2011
1	Aldo-Keto Reductase Family 1 Member C3IBA 09/2011
1	Oxidoreductases (Dehydrogenase)IBA 09/2011
1	SpermineIBA 08/2011
1	PolyaminesIBA 08/2011

Therapy/Procedure

7	Therapeutics 07/2017 - 01/2011
1	Immunotherapy 11/2016
1	Radiotherapy 05/2013
1	Drug Therapy (Chemotherapy) 05/2013